MycoWeekly Newsletter

Your Weekly Dose of Mycology Research

Detoxification of coumarins by rumen anaerobic fungi: insights into microbial degradation pathways and agricultural applications

2025-04-17
Journal of Animal Science and Biotechnology • Level 1 (6 panels)
Yuqi Li, Jian Gao, Yaxiong Cao, Xinming Cheng, Zhanying Sun, Jiyu Zhang, Weiyun Zhu, Martin Gierus, Yanfen Cheng

Coumarins, toxic phytochemicals that hinder nutrient cycling, have now been shown to be degraded by rumen anaerobic fungi. This study reveals Pecoramyces ruminantium F1's ability to metabolize coumarin into less harmful compounds through alpha/beta hydrolases and NAD(P)H oxidoreductases, offering new prospects for sustainable agriculture via fungal detoxification.

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qPCR-Based Molecular Detection of Trichophyton indotineae by Targeting Divergent Sequences

2025-04-01
Mycopathologia • Level 1 (6 panels)
Engin Kaplan, Oğuzhan Bingöl, Hazal Kandemir, Ayşe Sultan Karakoyun, Murat Durdu, Macit Ilkit

A new study on Trichophyton indotineae, a dermatophyte known for treatment resistance, introduces a qPCR-based diagnostic method targeting a distinct 499 bp sequence. This assay demonstrated 93.3% sensitivity and 100% specificity, offering an effective tool for accurate identification in mycology labs without relying on ITS single nucleotide polymorphisms.

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Molecular Characterisation of the Peroxidase Gene Family in Botrytis cinerea and the Role of BcPRD7 in Virulence

2025-04-01
Molecular plant pathology • Level 1 (6 panels)
Shixuan Zhang, Jialin Wang, Bai Li, Jinping Zang, Hongzhe Cao, J. Xing, Jingao Dong, Kang Zhang

This study explores the peroxidase gene family in Botrytis cinerea, highlighting BcPRD7's pivotal role in virulence. Key findings reveal BcPRD7 influences oxidase activity, stress responses, and pathogen development via Woronin body interactions. This research provides a framework for novel strategies in managing B. cinerea-related plant diseases.

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Trends of Azole-Resistant Aspergillus Fumigatus Susceptibility Over 12 Years from a German ECMM Excellence Center

2025-04-01
Mycopathologia • Level 1 (6 panels)
H. Verhasselt, Lara Thissen, Ulrike Scharmann, S. Dittmer, P. Rath, Joerg Steinmann, L. Kirchhoff

This study from a German ECMM Center assesses trends in azole-resistant Aspergillus fumigatus (ARAf) susceptibility. Over 12 years, 143 ARAf isolates reveal stable MICs for itraconazole and voriconazole but increased resistance mutations like TR46/Y121F/T289A post-2016, underscoring evolving antifungal resistance profiles.

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