MycoWeekly Newsletter

Your Weekly Dose of Mycology Research

Production of nitroaryl secondary metabolites by wood-decaying fungi of Phlebia spp.

2025-12-09
Mycologia • Level 2 (6 panels)
Eero A. Kiviniemi, M. Wahlsten, J. Jokela, Taina Lundell

In the study of white rot fungi of the genus Phlebia, researchers identified novel nitroaryl secondary metabolites, specifically 6-nitroveratryl alcohol and 4-nitroveratrole. These compounds, produced in low-nitrogen conditions, suggest complex biosynthetic pathways involving both nitrate and ammonium ions, challenging prior understanding of lignin degradation in these efficient wood decomposers.

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rDNA copy number variation affects yeast fitness in response to different environments.

2025-05-03
Genetics • Level 2 (7 panels)
Kevin Thornton, Elizabeth X. Kwan, K. Bubb, Luana Paleologu, M. K. Raghuraman, B. J. Brewer, Josh T. Cuperus, C. Queitsch

Ribosomal DNA (rDNA) copy number variation, an essential genomic trait, significantly affects yeast adaptability. New research demonstrates that selective pressures maintain rDNA at approximately 100 copies in yeast, with higher copy numbers providing enhanced resilience under environmental stress. These findings illuminate rDNA's critical role in ecological fitness strategies of yeast.

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Characterization of fungal communities transmitted from sow to piglet.

2025-08-25
Microbiology spectrum • Level 2 (7 panels)
Jinping Fan, Mengzhen Song, Yanguang Ling, Zhifeng Wu, Wen Xiong, Shiyu Tao, Yaoqin Shen

This study delves into the vertical transmission of gut fungal communities from sows to piglets, using ITS1 rRNA sequencing to analyze samples. It reveals that sow feces harbor the most diverse fungal communities, with Ascomycota and Basidiomycota dominating across groups. FEAST analysis shows substantial transmission from sow feces to piglet feces, highlighting core fungi's role in early-life microbiota development.

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Diagnosis of invasive pulmonary aspergillosis using metagenomic next-generation sequencing and conventional microbial tests post-COVID-19 pandemic

2025-06-09
Microbiology spectrum • Level 2 (7 panels)
Ping Li, Yuxia Chen, Xuelei Cao, Zheying Wang, Lintao Sai, Lili Wang

This study evaluates the efficacy of metagenomic next-generation sequencing (mNGS) in diagnosing invasive pulmonary aspergillosis (IPA) post-COVID-19. mNGS outperforms conventional microbial tests, showing 80.58% sensitivity. COVID-19 history emerges as an independent IPA risk factor, highlighting the need for vigilant follow-up. Mixed infections, frequently involving Human gammaherpesvirus, are prevalent in IPA patients.

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